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Ubudlelwano phakathi kwe-HIV kanye le-STI kuhamba konke kokubili : nxa ule-STI manengi amathuba okuthi uthole futhi uyidlulisele nge-HIV. Ukuze uzwisise ukuthi kungani lokhu kuqakathekile kumele uzwisise ukuthi i-HIV ihlangana kanjani lendlela umzimba wakho osabela ngayo ezifweni.

  Nxa uthola i-STI, umzimba wakho udala ama-CD4 cells ukuze alwe laleli gcikwane.Amaseli e-CD4 angamaseli i-HIV ewadingayo ukuze iphile futhi izenzele amakhophi ayo. Nxa uhlangana le-HIV ngesikhathi umzimba wakho uzama ukulwa lesinye isifo esithathelwana ngocansi, igcikwane manengi amathuba okuba likwazi ukuthola futhi lithelele i-CD4 cell. Lokhu kusiza i-HIV izenzele ikhaya ngaphakathi emzimbeni wakho futhi iqale ukusabalalisa igcikwane kwamanye amaseli.

  Futhi, lokhu kungenxa yokuthi lapho umzimba wakho uthola i-STI entsha, uzokwakha amaseli e-CD4 engeziwe ukulwa laleli gcikwane.Lokhu kutsho ukuthi i-HIV esivele isemzimbeni wakho izoba lethuba elengeziwe lokusabalala lokuphindaphindeka, ithelele amaseli e-CD4 amatsha afika endaweni ezolwa le-STI. Kuphinde kucuphe amaseli e-CD4 asevele ethelelekile ukuthi aqale ukwenza enye i-HIV, njengoba ecutshwa ukuze azame ukulwa nesifo esisha.

Nokho, nxa ubambelela ekwelatshweni ngezidambisagcikwane futhi ulegcikwane elingabonakali, ucwayisiso selukhombisile ukuthi  ukuhlangana  leyinye i-STI ngeke kwengeze umthamo wegcikwane egazini, njengoba ukwelatshwa kwakho kuvimbela i-HIV ukuthi ingakwazi ukwenza amakhophi adingekayo ukusabalalisa isifo.

Ezinye izifo zocansi lazo zidala izilonda noma ukusikeka ezithweni zakho. Lokhu kunganikeza indawo yokungena kalula ye-HIV, ukuze ingene iphinde iphume kalula emzimbeni wakho.

Abantu abale-HIV abangatholi ukwelatshwa okuphumelelayo balamathuba amanengi okuthola ezinye izifo ezithathelwana ngocansi futhi ngokuvamile bazoba lezimpawu ezinzima kakhulu. Lokhu kungenxa yokuthi amasotsha omzimba abo awakwazi ukulwa laleli gcikwane ngokuphumelelayo, okutsho ukuthi izifo zocansi zingathuthuka ngokuphangisa, zisakazeke futhi zibe zimbi kakhulu. 

  Okokugcina, i-HIV lezinye izifo zocansi zidluliselwa ngocansi olungavikelekanga. Ngakho-ke ukuziphatha okufanayo okungandisa ingozi yokuthola i-HIV lakho kukwenza abe manengi amathuba okuthola ezinye izifo zocansi. Lokhu kuhlanganisela  ukuba labalingani abanengi  bamacansi, lokungawasebenzisi njalo amakhondomu. Nxa kutholakale ukuthi uke waba le-STI ngemuva nje, kuyanconywa ukuthi lawe uhlolwe i-HIV.

Yebo, lakuba ezinye izifo ezithathelwana ngocansi zisemathubeni amanengi okuthi zidluliselwe ngocansi lomlomo kulezinye. Ezinye zezifo ezithathelwana ngocansi ezivame ukudluliselwa ngocansi lomlomo yi-herpes, i-gonorrhea kanye le-syphilis, kodwa ezinye izifo zocansi zingadluliselwa ngomlomo.

Maningi amathuba okuthola izifo ezithathelwana ngocansi ngocansi lomlomo uma umuntu owenza ucansi lomlomo elomphimbo obuhlungu noma ukusikeka, izilonda noma izilonda emlonyeni noma ezindebeni zakhe. Ngokufanayo, nxa umuntu ocansini lomlomo elezilonda noma ukusikeka emuva noma ezithweni , ingozi yokutheleleka iyanda. Ukusebenzisa ikhondomu noma iDental dam ukwenza ucansi lomlomo kuzonciphisa ingozi yokutheleleka.